Статья
ОСНОВНЫЕ НАПРАВЛЕНИЯ МОДИФИКАЦИИ ПОВЕРХНОСТИ МЕТАЛЛИЧЕСКИХ ЭНДОВАСКУЛЯРНЫХ СТЕНТОВ В РЕШЕНИИ ПРОБЛЕМЫ РЕСТЕНОЗОВ (ОБЗОР 1 ЧАСТЬ
Рестенозы металлических стентов, возникающие после имплантации, остаются нерешенной проблемой и существенно ограничивают их терапевтическую эффективность. В обзоре освещены наиболее перспективные с точки зрения физиологии и клеточной биологии варианты модификации металлических поверхностей, представлены преимущества и недостатки каждого из методов. В первую часть обзора включены направления, касающиеся разработки стентов с антитромботическим и антипролиферативным покрытием, так же представлены наиболее значимые и интересные исследования, направленные на формирование на поверхности стентов эндотелиального слоя in vitro.
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