Статья
Роль SNP-маркеров хромосомы 10 в патогенезе фибрилляции предсердий
Фибрилляция предсердий (ФП) — одна из самых распространенных тахиаритмий, вклад в возникновение которой вносят как факторы среды, так и генетические факторы, четкие представления о которых могут быть чрезвычайно важны для определения тактики лечения и прогнозирования течения заболевания. В статье представлен краткий обзор исследований генетических предикторов ФП, в частности SNP-маркеров, обнаруженных на хромосоме 10. Установление связи выявленных SNP хромосомы 10 с функциональными генами, изменение структуры или регуляции которых может повлиять на развитие ФП, приоткрывает завесу понимания механизмов влияния данных SNP на патогенез ФП.
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