Статья
ПРИМЕНЕНИЕ АНТИАРИТМИЧЕСКИХ СРЕДСТВ У ПОЖИЛЫХ ПАЦИЕНТОВ. ПРЕПАРАТЫ I И II КЛАССА ПО КЛАССИФИКАЦИИ ВОГАНА-ВИЛЬЯМСА
Применение антиаритмических препаратов I класса у пожилых пациентов ограничивают их нежелательные реакции, аритмогенное действие (I A и I C) и высокий риск лекарственных взаимодействий. Применения дизопирамида следует избегать из-за выраженных антихолинергических свойств, сопряженных с риском развития когнитивных и соматических расстройств и падений у самых пожилых пациентов. Имеющиеся данные позволяют предположить, что у пожилых лиц нет существенных ограничений к применению β-адреноблокаторов. Однако для определения препаратов данной группы с оптимальным соотношением польза/риск у лиц пожилого возраста с коморбидностью необходимы дальнейшие исследования.
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