Статья
Возможности использования микроРНК в качестве биомаркера при диагностике инсульта
Острое инсульт-индуцированное повреждение эндотелиальных клеток приводит к нарушению мозговой микроциркуляции и значительному повреждению ткани головного мозга. Несмотря на недавний прогресс терапии, способствующий повышению выживаемости после инсульта, диагностические подходы, направленные на раннюю точную идентификацию патогенетического подтипа, остаются ограниченными. МикроРНК являются перспективными кандидатами на роль новых биомаркеров инсульта. Настоящая статья посвящена обзору данных о связи инсульта с изменением уровней определенных циркулирующих микроРНК и перспективах их диагностического использования.
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