Кандесартана цилексетил в превентивной терапии сердечно-сосудистых заболеваний

А. Я. Ивлева

Статья

Кандесартана цилексетил в превентивной терапии сердечно-сосудистых заболеваний

А. Я. Ивлева

2007

Эффективность и хорошая переносимость блокаторов ангиотензиновых рецепторов при артериальной гипертонии (АГ) доказаны в рандомизированных, широкомасштабных, клинических исследованиях. Установлены существенные фармакодинамические различия между препаратами, блокирующими ангиотензиновые рецепторы, что имеет потенциально важное клиническое значение. Доказано преимущество кандесартана по степени и длительности снижения артериального давления (АД) при АГ и уменьшение частоты сердечно-сосудистых осложнений при длительном лечении АГ кандесартаном. Благоприятное влияние кандесартана на метаболизм отмечено у пациентов с сахарным диабетом, независимо от антигипертензивного эффекта. В контролируемых исследованиях с применением кандесартана при хронической сердечной недостаточности полностью доказана их эффективность как в комплексной терапии при назначении кандесартана в комбинации с E-адреноблокатором, так и при дополнительном присоединении к комбинации E-адреноблокатора с ингибитором ангиотензин-превращающего фермента.

Ивлева А. Я. Кандесартана цилексетил в превентивной терапии сердечно-сосудистых заболеваний. Кардиоваскулярная терапия и профилактика. 2007;6(6):83-90.

Цитирование

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А. Я. Ивлева ФГУ «Поликлиника №3» Управления делами Президента РФ, Москва

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Кардиоваскулярная терапия и профилактика

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