Статья
Как сохранить приверженность к приему антикоагулянта у пациента с фибрилляцией предсердий?
Менее обременительное, по сравнению с варфарином, лечение прямыми пероральными антикоагулянтами (ППОАК) способно привести к лучшей приверженности к терапии больных с фибрилляцией предсердий (ФП). Однако у определенного числа пациентов с ФП, которым рекомендовались ППОАК, рецидивирует кардиоэмболический инсульт, что в значительной степени связано с невыполнением больными врачебных рекомендаций. Назначение ППОАК в качестве препаратов первой линии не гарантирует высокую приверженность больных с неклапанной ФП. Для пациентов с ФП пожилого и старческого возраста с многочисленными сопутствующими заболеваниями предложение более простой схемы фармакотерапии особенно актуально. В ряде крупных современных исследований, выполненных в клинической практике, установлена высокая приверженность к терапии ривароксабаном, которая может быть следствием приема данного ППОАК 1 раз в сутки, его безопасности и эффективности.
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