Статья
Особенности коронарного атеросклероза
В обзоре представлены современные аспекты этиологии и патогенеза атеросклероза. Показана роль воспалительных клеток, компонентов клеточного ответа при аллергических реакциях, нарушения углеводного обмена, клеточного старения, инфекции на различных этапах формирования атеросклеротической бляшки. Акцентировано внимание на особенностях атеросклероза и кальциноза коронарных артерий (КА). Показано влияние возраста и пола на течение данного заболевания. Приведены сведения о важной роли миокардиальных мостиков в изменении гемодинамики в сегментах КА. Представленные данные свидетельствует о том, что различия локализации атеросклеротического поражения в системах правой и левой КА связаны с гемодинамическими, анатомическими и физиологическими особенностями. Обоснована большая уязвимость в этом отношении передней межжелудочковой артерии.
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