Статья
Активность симпатической нервной системы и уровень лептина у пациентов с ожирением и синдромом обструктивного апноэ/гипопноэ во сне
Целью настоящего исследования было изучение активности симпатической нервной системы (СНС) и уровня лептина у пациентов с ожирением в зависимости от наличия или отсутствия синдрома обструктивного апноэ/гипоноэ во время сна(СОАГС). Для этого было обследовано 75 пациентов с СОАГС и 40 сопоставимых по возрасту, массе тела, ИМТ, уровню артериального давления пациентов без нарушений дыхания во время сна. Было выявлено, что пациенты с СОАГС характеризуются более значимым повышением активности СНС, которое помимо повторных эпизодов гипоксии/гиперкапнии ассоциировано с более выраженным андроидным ожирением и повышением уровня лептина в сыворотке крови.
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