Статья
ЭФФЕКТИВНОСТЬ И БЕЗОПАСНОСТЬ ГИПОЛИПИДЕМИЧЕСКИХ ПРЕПАРАТОВ В КАЧЕСТВЕ СРЕДСТВ ПЕРВИЧНОЙ И ВТОРИЧНОЙ ПРОФИЛАКТИКИ СЕРДЕЧНО-СОСУДИСТЫХ ЗАБОЛЕВАНИЙ У ЛИЦ ПОЖИЛОГО ВОЗРАСТА
Рассматривается влияние гиперлипидемии на заболеваемость и смертность пожилых пациентов. Также освещаются вопросы эффективности и безопасности гиполипидемических средств в первичной и вторичной профилактике сердечно-сосудистых заболеваний у пациентов ≥80 лет, представляющих собой самую быстрорастущую группу населения и имеющую наиболее высокий сердечно-сосудистый риск. Подчеркивается необходимость учета полиморбидности и полипрагмазии повышающих риск развития нежелательных реакций, обусловленных как собственно статинами, так и их лекарственными взаимодействиями, что требует оценки соотношения риск/польза. Кроме того, необходима разработка надежных инструментов прогнозирования релевантных исходов (например, инсульта, инвалидности, снижения качества жизни) и оценки рациональности гиполипидемической терапии у пожилых больных, а также их приверженности лечению.
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