Статья
НОВЫЕ МЕТОДЫ ОЦЕНКИ СУБКЛИНИЧЕСКИХ ИЗМЕНЕНИЙ СЕРДЕЧНО-СОСУДИСТОЙ СИСТЕМЫ ПРИ АРТЕРИАЛЬНОЙ ГИПЕРТОНИИ
Сердце анатомически и функционально связано с системой сосудов. Структурные и функциональные изменения в артериальном русле увеличивают постнагрузку на левый желудочек (ЛЖ) и могут изменять его функцию, приводя к адаптационной структурной перестройке ЛЖ. Систолическое артериальное давление (САД) в аорте, отражающее непосредственную нагрузку на ЛЖ, существенно отличается от САД в плечевой артерии за счет задержки появления отраженной волны в аорте. Левожелудочково-артериальное взаимодействие – концепция, которая помогает понять различные варианты «оптимального» функционирования сердечно-сосудистой системы, последствия изменений в артериальном русле для функции сердца. В обзоре приводятся методы анализа левожелудочково-артериального взаимодействия, клинические последствия его нарушения и эффекты антигипертензивной терапии, приводятся результаты собственных исследований.
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