Статья
ОКСИДАТИВНЫЙ СТРЕСС И ВОЗМОЖНОСТИ ЕГО КОРРЕКЦИИ ИНГИБИТОРАМИ АНГИОТЕНЗИНПРЕВРАЩАЮЩЕГО ФЕРМЕНТА У БОЛЬНЫХ ИНФАРКТОМ МИОКАРДА В СОЧЕТАНИИ С САХАРНЫМ ДИАБЕТОМ 2 ТИПА
В обзоре освещены современные представления о механизмах нарушения функции сердечно-сосудистой системы у больных с сахарным диабетом 2 типа. Особое внимание уделено роли оксидативного стресса в развитии ишемии миокарда, реперфузионного синдрома, эндотелиальной дисфункции, атерогенеза. Приведены данные, указывающие, что современный ингибитор ангиотензинпревращающего фермента, зофеноприл, обладает не только высокой кардио- и вазопротективной активностью, но и дополнительными антиоксидантными свойствами, что позволяет использовать его у больных ишемической болезнью сердца и сахарным диабетом.
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