Статья
ЭФФЕКТИВНОСТЬ И БЕЗОПАСНОСТЬ ПРИМЕНЕНИЯ АЦЕТИЛСАЛИЦИЛОВОЙ КИСЛОТЫ В ПЕРВИЧНОЙ И ВТОРИЧНОЙ ПРОФИЛАКТИКЕ СЕРДЕЧНО-СОСУДИСТЫХ ЗАБОЛЕВАНИЙ
Освещены вопросы, касающиеся применения ацетилсалициловой кислоты (АСК) в первичной и вторичной профилактике сердечно-сосудистых заболеваний. Обсуждаются дазагрегационные механизмы действия АСК. Представлены данные об эффективности и безопасности применения препаратов АСК с целью первичной и вторичной профилактики, полученные в рандомизированных контролируемых исследованиях. Обозначены основные группы пациентов, которые нуждаются в назначении АСК с профилактической целью согласно современным клиническим рекомендациям. Рассматривается баланс между пользой и риском, связанным с её приемом, и способы повышения безопасности антиагрегантной терапии, в том числе за счет использования кишечно-растворимых форм АСК.
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