Статья
Дисфункция эндотелия при артериальной гипертензии: причина или следствие?
Артериальная гипертензия продолжает оставаться пандемией XXI века, являясь основным фактором развития преждевременной смерти. Внедрение визуализирующих методов обследования в клиническую практику выявило высокую распространенность поражения “органов-мишеней”, опосредованного гипертензией. Одним из системных “органов-мишеней” при артериальной гипертензии является эндотелий, повреждение которого играет важную роль в инициации сердечно-сосудистого континуума. С другой стороны, нарушение структуры и функции эндотелия рассматривается как возможная причина повышения артериального давления. В этой статье систематизированы данные о причинно-следственной связи между артериальной гипертензией и эндотелиальной дисфункцией, и рассматривается направление дальнейшего изучения функции сосудистого эндотелия.
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