Роль вазодилатирующих β-адреноблокаторов в контроле артериальной гипертензии и снижении риска сердечнососудистых и цереброваскулярных осложнений

Я. Н. Базиль

Статья

Роль вазодилатирующих β-адреноблокаторов в контроле артериальной гипертензии и снижении риска сердечнососудистых и цереброваскулярных осложнений

Я. Н. Базиль

2011

На протяжении нескольких десятилетий β-адреноблокаторы (β-АБ) продолжают играть ключевую роль в терапии артериальной гипертензии (АГ) и связанных с ней сердечно-сосудистых заболеваний (ССЗ). Согласно современным национальным рекомендациям, эти препараты остаются основой антигипертензивной терапии. По последним данным, терапия β-АБ ассоциируется с менее выраженным снижением общей смертности, смертности от ССЗ и частоты сердечно-сосудистых событий, по сравнению с лечением ингибиторами ренин-ангиотензиновой системы или антагонистами кальция. Следует отметить, что класс β-АБ включает в себя широкий спектр препаратов, и опасения о соотношении риска и пользы при приеме этих лекарственных средств могут не распространяться на вазодилатирующие β-АБ последнего поколения, такие как карведилол и небиволол. Постоянно растет число исследований, подтверждающих клиническую эффективность и безопасность вазодилатирующих β-АБ при АГ. Согласно результатам исследований конечных точек, эти препараты могут играть важную роль в снижении суммарного риска ССЗ у пациентов с сердечной недостаточностью — гипертензивного либо ишемического генеза.

Базиль Я. Н. Роль вазодилатирующих β-адреноблокаторов в контроле артериальной гипертензии и снижении риска сердечнососудистых и цереброваскулярных осложнений. Кардиоваскулярная терапия и профилактика. 2011;10(3):97-102.

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Я. Н. Базиль Программа сердечно-сосудистого здоровья Seinsheimer, Медицинский университет Южной Каролины и медицинский центр Ralph H. Johnson VA

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Кардиоваскулярная терапия и профилактика

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