Статья
Фибрилляция предсердий как фактор риска развития когнитивных нарушений и деменции. Возможности антикоагулянтной терапии в их профилактике
За последние годы накоплены данные относительно возможных ассоциаций между когнитивными нарушениями (КН) и фибрилляцией предсердий (ФП). Данная статья представляет обзор отечественной и зарубежной литературы, включающий современную классификацию КН, механизмы влияния ФП на снижение когнитивных функций и развитие деменции, рекомендации по профилактике КН у пациентов с ФП. Особое внимание уделено оценке когнитивного статуса и безопасной антикоагулянтной терапии, что является приоритетным в профилактике КН у пациентов с ФП. Анализ литературы показал большую эффективность и безопасность препаратов из группы прямых пероральных антикоагулянтов, в частности, ривароксабана по сравнению с варфарином, который может быть рекомендован пожилым пациентам с ФП для профилактики инсульта, КН и деменции.
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