Статья
Дефицит железа у пациентов кардиохирургического профиля и возможности его коррекции на этапе предоперационной подготовки
Среди пациентов кардиохирургического профиля распространенность железодефицитных состояний достигает 70 %, причем анемия выявляется менее чем в 50 % случаев. Вместе с тем не только анемия, но и латентный дефицит железа служат факторами риска неблагоприятных исходов у кардиохирургических пациентов и ассоциированы с высокой частотой и объемом гемотрансфузий и более длительным пребыванием пациентов в стационаре. Своевременная диагностика и коррекция дефицита железа, независимо от наличия анемии, являются обязательными на этапе предоперационной подготовки. Применение пероральных препаратов железа ограничивается их невысокой эффективностью у пациентов данной категории и повышенным риском развития нежелательных явлений. Внутривенные препараты железа обладают высоким потенциалом коррекции дефицита железа, а их эффективность и безопасность ранее доказаны. Применение карбоксимальтозата железа сопровождалось положительными эффектами в исследованиях коррекции дефицита железа у пациентов кардиологического и кардиохирургического профилей. У кардиохирургических больных применение препарата обеспечивает лучшие показатели динамики уровней ферритина и гемоглобина, снижение риска гемотрансфузий и уменьшение длительности пребывания в стационаре. Внутривенное введение карбоксимальтозата железа в предоперационном периоде у кардиохирургических пациентов может улучшить клинические результаты и экономическую эффективность кардиохирургических вмешательств.
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